After graduation, Rani began to work out as a researcher for BBC and various other organizations. Her hard work paid off when she was hired to host a live news and entertainment programme ‘The Edit’ on Channel Five in 2002. She presented numerous other pop shows like Spring Break Live, Pop City Live and Party in the Park on Five. She too was a freelancer reporter for 5 News on the same channel.
She fronted BBC Three’s current affair programme show ‘The State We’re In during Spring 2003 as well as hosted the first Poetry Slam. In March 2005, she joined British radio station called BBC Asian Network and presented weekend Hot Breakfast show. She also presented the morning talk show titled ‘Anita Rani’ on the same station for one year.
She was the co-host of BBC Two ‘Desi DNA’, an Art and Cultural show starting May 20, 2006. Rani served BBC Three late night show ‘Destination Three’ as a part of the launch team. In 2005, she became the regular reporter of The Cricket Show on Channel 4. In May 2006, she along with Simon Thomas co-presented the Saturday morning cricket based show named Cricket AM on Sky Sports.
She was the host of BBC News 24 show ‘MY Generation Next’ between 2 and 9 December 2006. In 2007 March and September, she filled for Anita Anand on weekday show on BBC Radio 5 Live. Rani was the presenter of World Have Your Say on BBC World Service, an international broadcaster. She has also covered shows for BBC Radio 6 Music.
Rani co-presented the BBC One ‘Rogue Restaurant in August 2008. Rani joined the members of roving reporters on The One Show to add more to her resume. On March 2, 2009, she joined BBC One and co-presented ‘Watchdog’ a British television series.
In 2011, Rani hosted a factual television show ‘Four Rooms’ which aired on Channel 4 on May 24, 2011. She was replaced by Sarah Benny in 2016. She along with Justin Rowlatt co-presented a documentary series titled ‘India on Four Wheels’. They traveled around the India and sample over the impacts that increasing usage of cars has in the country over last two decades. She then teamed up with Rowlatt on its second season entitled ‘China on Four Wheels’.
In 2013, Rani covered the Airport live project from Heathrow Airport. She was the part of ‘Russia on Four Wheels’ which aired on 20 and 22 January of 2014. In April 2014, she was one of the hosts of ‘Escape to the Continent’ on BBC Two.
She is currently the presenter of BBC’s weekly show ‘Country File’. She along with Robert Llewellyn and Dan Snow co-anchored BBC Two ‘The World’s Busiest Railway 2015’. In 2016, she co-hosted ‘The Refugee Camp: Our Desert Home’ as well as presented This Morning alongside James Martin for four Fridays after replaced by Dan Neal and Rylan Clark-Neal.
Rani alongside Ade Adepitan and Ant Anstead co-presented the BBC Two series ‘New York: America’s Busiest City’ in 2016. She even was the presenter of ‘My Family, Partition and Me: India 1947 on BBC One.
In 2015, Rani along with the dancing partner Gleb Savchenko participated the thirteen series of ‘Strictly Come Dancing’. she closely misses out the finale of the show. Rani enquired the history of her maternal grandfather Sant Singh in an episode of ‘Who Do You Think You Are? telecasted on BBC One on October 1, 2015. in 2017, she presented Strictly Tour around Britain replacing Mel Giedroyc.