She quickly went to Beverly Slopes Secondary School yet dropped out after her sophomore year, got a GED, and went ahead to get a degree in correspondence from College of California, San Diego. Vayntrub and Stevie Nelson collaborated to begin the gathering Live Wet blanket Young ladies, a gathering which delivers various parody shorts on YouTube including the "How about we Discuss Something Additionally Intriguing" series. Vayntrub has had little parts in film and TV, including Life happens, she has additionally featured in a few CollegeHumor videos.